Enhancing Medical Information Retrieval using RAG with Hybrid Vector Search and Query Expansion

Volume 19, Issue 1,  2025

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Author(s):

Irtiza Hussain* NED University of Engineering and Technolog, Karachi, Pakistan, irtizahussain221@gmail.com

Abstract The rise of large language models (LLMs) has improved people’s access to medical information. These LLMs, however, lack the domain-specific knowledge essential to answering more specialized questions. To plug this knowledge gap, this paper explores the use of retrieval-augmented generation. A comparative analysis of four different retrieval strategies — dense vector search, dense vector search with query expansion, hybrid vector search, and hybrid vector search with query expansion — was carried out and a combination of hybrid vector search with query expansion was found to be the most effective retrieval strategy. This framework will help efficient and cost effective information retrieval for chatbot used in the medical sector. At the same time, because of its generic nature, this proposed combination can be used for applications in other fields.
Keywords Retrieval-Augmented Generation, Hybrid Vector Search, Query Expansion, LLMs, Dense Vectors, Sparse Vectors
Year 2025
Volume 19
Issue 1
Type Research paper, manuscript, article
Journal Name Journal of Information & Communication Technology
Publisher Name ILMA University
Jel Classification -
DOI -
ISSN no (E, Electronic) 2075-7239
ISSN no (P, Print) 2415-0169
Country Pakistan
City Karachi
Institution Type University
Journal Type Open Access
Manuscript Processing Blind Peer Reviewed
Format PDF
Paper Link https://jict.ilmauniversity.edu.pk/journal/jict/19.1/4.pdf
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